Solid Tumours
You may also be interested in our brochure MLPA for Tumour Profiling (link opens in a new window).

Product NameApplicationRegion
ME001-Tumour suppressor mix 1basic research Tumour suppressor genes Various
ME002-Tumour suppressor mix 2basic research Tumour suppressor genes Various
ME011-MMRimproved Mismatch repair genes (MMR) MLH1 3p22.2; MSH2 2p21; MSH6 2p16.3; PMS2 7p22.1; EPCAM 2p21; BRAF V600E
ME024-9p21 Tumours, Cutaneous melanoma 9p21: CDKN2A, CDKN2B, and flanking genes
ME042-CIMPbasic research CpG Island methylator phenotype (CIMP) Various
P014-Chromosome 8 Tumour research Chr. 8
P027-Uveal melanoma Uveal melanoma (UM) Chr. 1p, 3, 6, 8
P047-RB1 Retinoblastoma (RB) RB1 13q14.2
P056-TP53CE Li-Fraumeni syndrome (LFS); (Tumour analysis for research use only) TP53 17p13.1
P063-FHIT-WWOX Diverse tumour types, epileptic encephalopathy FHIT (3p14.2) and WWOX (16q23.1)
P078-Breast tumour Breast tumour various
P088-Oligodendroglioma 1p-19q Oligodendroglioma 1p, 19q, IDH1/2, CDKN2A/2B
P105-Glioma-2 Glioma, malignant EGFR, TP53, PTEN + various other
P157-20q region Colon cancer, breast cancer and various others 20q (BCL2L1, MYBL2, ZNF217, DNMT3B, AURKA, GNAS)
P175-Tumour Gain Tumour Gain various
P181-Centromere mix 1 Centromeric screening Centromeres
P182-Centromere mix 2 Centromeric testing Centromeres
P215-EXT Multiple Osteochondromas EXT1 8q24, EXT2 11p11
P225-PTENCEimproved PTEN hamartoma tumor syndrome, Cowden syndrome, Bannayan-Riley-Ruvalcaba syndrome, PTEN-related proteus syndrome, Proteus-like syndrome; (Tumour analysis for research use only) PTEN 10q23.31
P251-NB mix 1 Neuroblastoma Chromosomes 1, 3 and 11
P252-NB mix 2 Neuroblastoma Chromosomes 2 (MYCN) and 17
P253-NB mix 3 Neuroblastoma Chromosomes 4, 7, 9, 12, 14
P258-SMARCB1 Rhabdoid tumors SMARCB1 22q11.2
P294-Tumour Loss Tumour Loss various
P298-BRAF-HRAS-KRAS-NRASbasic research Various tumour types BRAF, HRAS, KRAS, NRAS
P301-Medulloblastoma mix 1basic research Medulloblastoma Chr. 6, Chr. 14, Chr. 16, Chr. 17.
P302-Medulloblastoma mix 2basic research Medulloblastoma Chr. 2, Chr. 3, Chr. 7, Chr. 9
P303-Medulloblastoma mix 3basic research Medulloblastoma Chr. 1, Chr. 4, Chr. 5, Chr. 8, Chr. 10, Chr. 20
P308-MET Papillary renal carcinoma, various cancers MET 7q31, PTEN 10q23.31, LRRK2 12q12
P315-EGFR Tumours, solid EGFR 7p11
P323-CDK4-HMGA2-MDM2 Sarcoma and other tumour types Chromosome 12, MDM2, CDK4 and HMGA2 genes
P376-BRCA1ness BRCA1-like breast cancer profile various
P378-MUTYHCEMA MUTYH-associated polyposis (MAP); Polyposis syndrome, hereditary mixed (HMPS1) MUTYH 1p34.1; SCG5 15q13.3; GREM1 15q13.3
P380-Wilms' tumour Wilms' tumour various
P417-BAP1 Melanocytic tumours, mesothelioma BAP1, 3p21.1
P419-CDKN2A/2B-CDK4 Familial melanoma CDKN2A, CDKN2B, CDK4, MITF E318K
P429-SDHA-MAX Paraganglioma and pheochromocytoma 5p15.3 and 14q23.3
P433-ARID1A-ARID1B Neuroblastoma, ovarian cancer + various other tumour types + mental retardation ARID1A, ARID1B
P451-Chromosome 16 Breast cancer + various tumour types Chromosome 16
P455-LZTR1 Schwannomatosis 22q11.21
P458-Gastric cancer Gastric cancer various
P466-CDC73 HPT jaw tumour syndrome, familial hyperparathyroidism, parathyroid carcinoma CDC73
P472-SUFU Familial Medulloblastoma and Meningioma 10q24.32
P474-CD274-PDCD1LG2-JAK2new Various cancer types CD274 (PDL1), PDCD1LG2 (PDL2), JAK2 at 9p24.1
P476-ZNRF3 Adrenocortical tumours and other solid tumours ZNRF3, 22q12.1
P478-SMARCE1new Meningioma, Coffin-Siris syndrome SMARCE1, 17q21.2
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