Sample DNA
MRC-Holland offers various types of artificially made DNA samples. Artificial Duplication DNA is intended for validation purposes. Reference DNA is intended to help identify suitable reference samples. Binning DNA helps in the correct set up of bins for mutation-specific probes.

Please note that these SDs are not suitable as controls for techniques other than MLPA or for probemixes other than specified.

Jump straight to Artificial Duplication DNA, Reference DNA or Binning DNA.

Artificial Duplication DNA
Contains artificially-made duplications for one or more probes; intended for validation purposes. Volume: 100 μl (20 reactions). Artificial Duplication DNA is never supplied with the corresponding probemix, and can be ordered separately.

Probemix & VersionItem No.
ME011-B3 MMRSD027
P002-D1 BRCA1SD024
P003-D1 MLH1/MSH2SD027
P008-C1 PMS2SD027
P034-B1/B2 DMD-1SD026
P035-B1 DMD-2SD026
P036-E2/E3 Human TelomereSD025
P037-B1 CLL-1SD028
P038-B1 CLL-2SD028
P040-B1 CLLSD028
P043-D1 APCSD027
P045-B3/C1 BRCA2/CHEK2SD024
P047-C1/D1 RB1SD028
P069-B1/B2 Human TelomereSD025
P070-B2/B3 Human TelomereSD025
P072-C1 MSH6SD027
P077-A3 BRCA2SD024
P087-C1 BRCA1SD024
P090-A4/B1 BRCA2SD024
P096-A2/B1 MR-2SD025
P116-B1 SGCSD026
P175-A2/A3 Tumour GainSD028
P176-C1/C2 CAPN3SD026
P202-B1/B2 IKZF1SD028
P245-B1 MicrodeletionSD025
P248-B1 MLH1/MSH2 ConfirmationSD027
P268-A2 DYSFSD026
P290-B2 Prenatal MicrodeletionsSD025
P294-B1 Tumour LossSD028
P327-B1/B2 iAMP32-ERGSD028
P335-B1/B2 ALL-IKZF1SD028
P377-A1/A2 Hematologic malignanciesSD028
P378-C1 MUTYHSD027
P383-A1 T-ALLSD028

Reference DNA
Intended to help identify suitable reference samples. Volume: 100 μl (20 reactions). Reference DNA is sometimes supplied for free with the corresponding probemix, but not always (see table below). It can be ordered separately.

Probemix & VersionItem No.Supplied with Probemix?
P008-C PMS2SD019no
P021-A SMASD019no
P050-C1 CAHSD039yes
P060-B SMASD019no
P110-B2 FCGR-1SD038yes
P111-B2 FCGR-2SD038yes

Binning DNA
Intended to aid in correct peak assignment for mutation-specific probes. Volume: 30 μl (6 reactions). Binning DNA is always supplied for free with the corresponding probemixes, but can be ordered separately.

Probemix & VersionItem No.
ME012-A1 MGMT-IDH1-IDH2SD054
ME042-C CIMPSD029
P003-D MLH1/MSH2SD052
P038-A CLLSD009
P043-E APCSD022
P045-C BRCA2/CHEK2SD067
P051-D ParkinsonSD029
P052-D ParkinsonSD029
P056-C TP53SD029
P059-B DystoniaSD044
P088-C2 Oligodendroglioma 1p-19qSD054
P102-C HBBSD029
P103-B DPYDSD030
P116-B SGCSD030
P125-B1 MitochondriaSD065
P140-C HBASD031
P175-A Tumour GainSD029
P190-C CHEK2SD029
P199-B HEXASD030
P247-A Chemokine 2SD071
P255-A/B ALDOBSD030
P256-B FLCNSD032
P280-B SLC26A4SD071
P281-A RYR1 mix 1SD015
P282-A RYR1 mix 2SD016
P285-C LRP5SD030
P298-A BRAF-HRAS-KRAS-NRASSD029
P305-B AGXTSD030
P315-B EGFRSD006
P370-B BRAF-IDH1-IDH2SD043
P377-A Hematologic MalignanciesSD068
P378-C MUTYHSD022
P414-B MDSSD029
P419-A CDKN2A/2B-CDK4SD008
P432-A MYH9SD035
P436-A ANO5SD033
P437-B Familial MDS-AMLSD070
P520-A2 MPN mix 2SD057
P438-D2 HLASD058 and SD059
P460-A SMASD042
P473-A CTNSSD064

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